Scientific visualization of water surrounding a poorly soluble molecular cluster

WATER, MOLECULES & LIFE

Dissolve in water.
Make water work.

Learning from biological systems, we connect molecular design with practical applications.

About the Laboratory
Polysaccharide nanocapsules containing multiple guest molecules

POLYSACCHARIDE NANOMATERIALS

Make β-glucan
dissolve, carry, and function.

We develop materials for solubilizing and stabilizing poorly water-soluble functional compounds.

Explore this research
Betaine-like molecules altering the surrounding water network

BIOMOLECULAR CONTROL

Molecules that control
activity and stability.

Betaine derivatives are designed to improve the function and stability of enzymes and nucleic acids.

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Students conducting research in the laboratory

STUDY & GROW

Ask questions.
Test them yourself.

We connect chemistry with food, cosmetics, healthcare, diagnostics, and materials science.

Life in the Lab

OUR PHILOSOPHY

Learn from life.
Create through chemistry.
Connect to society.

We study the outstanding substances, structures, and mechanisms found in living systems at the molecular level. Drawing on organic chemistry, polymer chemistry, glycoengineering, analytical chemistry, and solution chemistry, we develop new molecules and materials and explore technologies for their practical use.

Our work ranges from fundamental molecular phenomena to applications in food, cosmetics, healthcare, diagnostics, and biotechnology.

Read about our philosophy ↗

RESEARCH AREAS

Research Areas

We create molecules, materials, and technologies by examining how water, biomolecules, and natural polymers behave.

01

Polysaccharide Nanomaterials

We transform β-glucan into materials that dissolve, carry, and function, with an emphasis on solubilizing and stabilizing poorly water-soluble compounds.

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02

Molecules Controlling Biomolecular Activity and Stability

Inspired by counterion compounds used by extremophiles, we develop betaine-derived additives that regulate enzyme and nucleic-acid function.

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03

Molecules that Alter Water Structure

We investigate how betaine derivatives influence aqueous environments and enable new approaches to dissolution and reactions in water.

In preparation ↗

FROM MOLECULES TO SOCIETY

From molecules
to practical impact.

We develop findings from fundamental chemistry into technologies that can be used in products and processes.

  1. 01Observe nature and needsDiscover
  2. 02Design molecules and materialsDesign
  3. 03Evaluate structure and functionEvaluate
  4. 04Develop applicationsImplement

RECENT TOPICS

Recent Topics

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Original illustration of betaine derivatives and hydration

PAPER · 2025

Hydrophilic ether-modified carboxybetaines for enzyme activation and stabilization

Ether modification improved aqueous solubility while preserving enzyme activation and enabling long-term stabilization under thermal and dilution stress.

Read the paper ↗

CONFERENCE · SEP 15–17, 2026

Presentation at the 78th Annual Meeting of the Society for Biotechnology, Japan

2Hp05
Extraction of flavonoids and hydrophobic components from mandarin peel using aqueous betaine-derivative solutions

Kansuke Arita, Takuma Nakai, and Kazuya Koumoto

Conference website ↗

JOIN OUR LAB

Develop answers
that do not yet exist.

Information for prospective undergraduate and graduate students, collaborators, and visitors.